No, the recommended dosage remains one tablet per day - the 365-tablet package simply provides an almost year-long supply in a single purchase, which is mainly practical and cost-effective, since you won't need to reorder the product frequently. The dose of 500 µg of methylcobalamin per tablet falls within the upper part of the range that a clinical dose-finding study links to 80-90% of the maximum effect in correcting lower B12 levels (Eussen et al., 2005), so taking a single tablet daily is fully sufficient for general maintenance use. If your doctor has advised a different dosage due to a diagnosed deficiency, follow their instructions.

The manufacturer explicitly states on the label that the product may contain traces of soy, milk and gluten-containing cereals, meaning it is not explicitly certified as a gluten-free product, but rather this is a precautionary statement about possible cross-contamination during production. If you have diagnosed celiac disease or a pronounced allergy to gluten, soy or milk, we advise against making this risk assessment on your own and recommend consulting your doctor before consuming this product, or choosing a product with a clearly certified gluten-free label. For people without a diagnosed allergy or with mild sensitivity, such traces typically do not pose a problem, but this is an individual assessment.

Sorbitol is a sugar alcohol commonly used in dietary supplements as a filler or bulking agent for tablets. It is not a classic sugar and has a lower glycemic index; however, when consumed in larger quantities (e.g., several dozen grams, as with some sugar-free candies), it is known that it can cause mild digestive disturbances such as bloating or a laxative effect. At the dose present in a single tablet of this product, the amount of sorbitol is far too low to cause such issues with normal use. If you have irritable bowel syndrome or another sensitivity to sugar alcohols, still pay attention to any bodily reactions when starting to use the product.

In terms of content, this is the same active ingredient at the same dose - 500 µg of methylcobalamin per day - so no significant difference in clinical effectiveness is to be expected between the two products. The main differences lie in the form (tablet vs. capsule), auxiliary ingredients (sorbitol vs. microcrystalline cellulose), and package size, which mainly affect the price per daily dose and practicality of use, but not the effectiveness of the vitamin B12 itself. Since the route of intake (oral) and dose in both correspond to clinically studied values, you can expect a comparable effect on maintaining normal B12 levels in the body (Eussen et al., 2005; Mazur et al., 2025).